Article
Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.
Human genetics - 1 Jun 1995
Kajii E, Umenishi F, Omi T, Ikemoto S
Abstract excerpt
The Rhesus (Rh) blood group system shows complex polymorphisms in the human. Some of the heterogeneity may be generated by alternative RNA splicing. For a systematic analysis of Rh-related mRNA isoforms expressed in reticulocytes, we isolated mRNA, which was then reverse transcribed and amplified...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Base Sequence
- Blood Proteins
- Cloning, Molecular
- DNA, Complementary
- Exons
- Genetic Variation
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Protein Conformation
- Reticulocytes
- Rh-Hr Blood-Group System
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid