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Article

Sequence analysis of cDNA derived from reticulocyte mRNAs coding for Rh polypeptides and demonstration of E/e and C/c polymorphisms.

Vox sanguinis - 1 Jan 1994

Simsek S, de Jong C A, Cuijpers H T, Bleeker P M, Westers T M, Overbeeke M A, Goldschmeding R, van der Schoot C E, von dem Borne A E

Abstract excerpt

RNA derived from enriched reticulocytes of Rh-phenotyped donors was isolated, reversely transcribed into cDNA and amplified with Rh-specific primers by polymerase chain reaction. Nucleotide sequence analysis of the entire coding region of the Rh cDNAs was carried out. Four types of cDNAs were identified, tentatively designated as RhSCI, RhSCII, RhSCIII and RhSCIV. Comparison of RhSCII with RhSCI (identical to the...

Topics

Amino Acid Sequence
Base Sequence
DNA, Complementary
Genetic Code
Humans
Isoantigens
Molecular Sequence Data
Peptides
Phenotype
Polymorphism, Genetic
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reticulocytes

Rh-Hr Blood-Group System

Source

Identifiers

PMID: 7801613
DOI: 10.1111/j.1423-0410.1994.tb01661.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7801613-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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