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Article

The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma.

The Journal of biological chemistry - 2 Jun 1995

Ji L, Arcinas M, Boxer L M

Abstract excerpt

We have identified an in vivo footprint over the PuF site on the translocated c-myc allele in Burkitt's lymphoma cells. The PuF site on the silent normal c-myc allele was unoccupied. We demonstrated by electrophoretic mobility shift assay, electrophoretic mobility shift assay with antibody, UV cross-linking followed by SDS-gel electrophoresis, and Western analysis that Nm23H2 in B cell nuclear extracts bound to...

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Identifiers

PMID: 7768941
DOI: 10.1074/jbc.270.22.13392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 8 closest

The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma.PMID 7768941Read ↗

Human c- <i>myc</i> Transcription Factor PuF Identified as nm23-H2 Nucleoside Diphosphate Kinase, a Candidate Suppressor of Tumor MetastasisSemantic proximity Read ↗

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NF-kappa B activity is required for the deregulation of c-myc expression by the immunoglobulin heavy chain enhancer.Semantic proximity Read ↗

The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII.Semantic proximity Read ↗

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