Article
[Molecular mechanisms of mutagenesis caused by apurinic/apyrimidinic DNA sites].
Genetika - 1 Jan 1991
Ivanov E L
Abstract excerpt
The subject of this review are molecular mechanisms and specificity of mutagenesis induced by apurinic/apyrimidinic (AP) sites representing a characteristic group of so called non-coding DNA lesions. The data available suggest that efficiency and specificity of AP sites-induced mutations depend, primarily, on genome structural organization. This is manifested in existence of DNA sequences highly prone to...
Topics
- DNA
- DNA Damage
- DNA Repair
- Mutagenesis
- Mutation
- SOS Response, Genetics