Article
Tumor suppressor activity of the gene encoding mammary-derived growth inhibitor.
Cancer research - 1 Jun 1995
Huynh H T, Larsson C, Narod S, Pollak M
Abstract excerpt
The gene encoding mammary-derived growth inhibitor (MDGI), a protein previously purified from bovine mammary gland and shown to have modest antiproliferative activity for human breast cancer cells in vitro, is demonstrated to function as a potent tumor suppressor gene. Human breast cancer cells t...
Topics
- Animals
- Breast
- Breast Neoplasms
- Carrier Proteins
- Chromosome Mapping
- DNA, Complementary
- Fatty Acid Binding Protein 3
- Fatty Acid-Binding Proteins
- Gene Expression
- Genes, Tumor Suppressor
- Humans
- Immunohistochemistry
- In Situ Hybridization, Fluorescence
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Peptides
- Phenotype