Cognitive scores in carriers of Huntington's disease gene compared to noncarriers.

doi:10.1002/ana.410370516

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Article

Cognitive scores in carriers of Huntington's disease gene compared to noncarriers.

Annals of neurology - 1 May 1995

Foroud T, Siemers E, Kleindorfer D, Bill D J, Hodes M E, Norton J A, Conneally P M, Christian J C

Abstract excerpt

Huntington's disease (HD) is a progressive neurodegenerative disorder recently shown to be due to an excess number of CAG trinucleotide repeats in the 5' translated region of chromosome 4. One of the cardinal features of HD is cognitive decline. While mental deterioration is obvious later in the...

Topics

Adult
Alleles
Cognition
Female
Heterozygote
Humans
Huntington Disease
Male
Middle Aged
Multivariate Analysis
Neuropsychological Tests
Polymerase Chain Reaction

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