Article
Cognitive scores in carriers of Huntington's disease gene compared to noncarriers.
Annals of neurology - 1 May 1995
Foroud T, Siemers E, Kleindorfer D, Bill D J, Hodes M E, Norton J A, Conneally P M, Christian J C
Abstract excerpt
Huntington's disease (HD) is a progressive neurodegenerative disorder recently shown to be due to an excess number of CAG trinucleotide repeats in the 5' translated region of chromosome 4. One of the cardinal features of HD is cognitive decline. While mental deterioration is obvious later in the disease course, the time of its onset is difficult to determine precisely. A sample of at-risk individuals without...
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