Motor unit behavior in canine motor neuron disease.

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Article

Motor unit behavior in canine motor neuron disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 May 1995

Pinter M J, Waldeck R F, Wallace N, Cork L C

Abstract excerpt

Hereditary canine spinal muscular atrophy (HCSMA) is an autosomally dominant disease of motor neurons that shares many pathological features with human motor neuron disease. A particularly striking feature of the affected, accelerated phenotype (homozygous HCSMA) is that profound weakness develops before appreciable motor neuron cell death occurs (Cork et al., 1989a), implying that motor unit functional defects...

Topics

Action Potentials
Aging
Animals
Axons
Dog Diseases
Dogs
Electric Stimulation
Electromyography
Genotype
Homozygote
Humans
Motor Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle Fibers, Skeletal

Muscle, Skeletal

Muscular Atrophy, Spinal

Phenotype

Reference Values

Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 7751923
PMCID: PMC6578257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7751923-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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