Article
Molecular heterogeneity of fluconazole-resistant and -susceptible oral Candida albicans isolates within a single geographic locale.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2002
Dassanayake R S, Ellepola A N B, Samaranayake Y H, Samaranayak L P
Abstract excerpt
The emergence of drug-resistant Candida albicans in immunocompromised patients is common. A disconcerting aspect of this phenomenon is the rapid emergence of C. albicans strains that are resistant to a widely used azole drug, fluconazole (FLZ). To understand the origin of FLZ-resistant yeast isolates, we investigated molecular profiles of 20 geographically related oral C. albicans isolates using three genotyping...
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