Article
Neutral polymorphisms in the deletion-prone regions of the dystrophin gene.
Human heredity - 1 Jan 2000
Zietkiewicz E, Akalin N, Labuda D
Abstract excerpt
The single-strand conformational polymorphism technique was used to search for neutral polymorphisms in 18 PCR-amplified dystrophin gene fragments. Out of the seven polymorphisms (six intronic and one exonic) detected in Caucasians, one was absent from the Oriental population. Significant differences in allele frequencies between the two populations were observed for three of the intronic polymorphisms. In...
Topics
- Alleles
- Asian People
- Dystrophin
- Gene Frequency
- Humans
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational
- White People