Article
Hepatitis C virus (HCV) genotype, tissue HCV antigens, hepatocellular expression of HLA-A,B,C, and intercellular adhesion-1 molecules. Clues to pathogenesis of hepatocellular damage and response to interferon treatment in patients with chronic hepatitis C.
The Journal of clinical investigation - 1 May 1995
Ballardini G, Groff P, Pontisso P, Giostra F, Francesconi R, Lenzi M, Zauli D, Alberti A, Bianchi F B
Abstract excerpt
To obtain information on the mechanisms of hepatocellular damage and the determinants of response to interferon, hepatitis C virus (HCV) genotype, tissue HCV antigens, hepatocellular expression of HLA-A,B,C and intercellular adhesion-1 molecules, and the number of lobular T lymphocytes were studied in 38 anti-HCV-positive patients. 14 patients did not show a primary response to interferon treatment. HCV genotype...
Topics
- Antigens, Viral
- Biopsy
- Cytotoxicity, Immunologic
- Female
- Genotype
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- Hepacivirus
- Hepatitis C