Article
Detection and typing of hepatitis C RNA in liver biopsies and its relation to histopathology.
Virchows Archiv : an international journal of pathology - 1 Dec 1996
Cathomas G, McGandy C E, Terracciano L M, Gudat F, Bianchi L
Abstract excerpt
This paper describes the correlation of hepatitis C genotypes detected in liver tissue with histological grading (inflammatory activity) and staging (degree of fibrosis/cirrhosis). The viral genotype was analysed by type-specific polymerase chain reaction (PCR) and correlated with histology and age of patients. In 69 patients with chronic hepatitis C (HCV) infection, genotypes 1a and 1b were detected in 13...
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