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Article

Abnormal structure and co-operative binding of low-density lipoprotein receptors containing the Glu-80-->Lys mutation.

Biochimica et biophysica acta - 6 Apr 1995

Patel D D, Soutar A K, Knight B L

Abstract excerpt

The properties of low-density lipoprotein (LDL) receptors containing a Glu to Lys substitution at position 80 have been studied in fibroblasts from a homozygous familial hypercholesterolaemic subject (MB) and in monkey COS cells transfected with the mutant cDNA. Receptors containing the Glu-80-->...

Topics

Animals
Binding Sites
Cell Line
Cells, Cultured
Glutamic Acid
Haplorhini
Humans
Hyperlipoproteinemia Type II
Lysine
Mutagenesis, Site-Directed
Mutation
Neuraminidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pronase

Receptors, LDL

Source

Identifiers

PMID: 7734445
DOI: 10.1016/0005-2760(94)00243-r

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7734445-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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