The psychopharmacological basis of nicotine's differential effects on behavior: individual subject variability in the rat.

doi:10.1007/BF02196927

Back to search

Article

The psychopharmacological basis of nicotine's differential effects on behavior: individual subject variability in the rat.

Behavior genetics - 1 Mar 1995

Rosecrans J A

Abstract excerpt

Nicotine, the presumed active pharmacological agent in tobacco, produces variable effects on behavior that are at best described as "paradoxical" in nature. Thus, nicotine, via tobacco use in humans or nicotine administration in experimental animals, tends to transpose behavior depending on predr...

Topics

Acetylcholine
Animals
Behavior, Animal
Dose-Response Relationship, Drug
Drug Tolerance
Female
Genetic Variation
Male
Nicotine
Rats
Rats, Inbred F344
Rats, Inbred SHR
Rats, Sprague-Dawley
Receptors, Nicotinic
Serotonin
Up-Regulation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.