Article
[Drug resistance, oncogenes, and anti-oncogenes in epithelial tumors].
Bulletin du cancer - 1 Dec 1994
Riva-Lavieille C
Abstract excerpt
Twenty four squamous cell carcinomas of the head and neck (HNSCC) of stage II to IV were evaluated for the expression of potential markers such as oncogenes and tumor suppressor genes in drug-resistance behavior. We have analysed the c-myc, c-jun, c-raf and N-ras and p53 expression in total RNA preparation from tumor biopsies obtained before treatment. The patients underwent chemotherapy including 5-fluorouracil...
Topics
- Biomarkers, Tumor
- Carcinoma, Squamous Cell
- Cell Line
- Epithelium
- Gene Expression
- Genes, fos
- Genes, jun
- Genes, myc
- Genes, p53
- Head and Neck Neoplasms
- Humans
- Mutation
