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Article

HB Gouda [alpha 72(EF1)His-->Gln], a new silent alpha chain variant.

Hemoglobin - 1 Feb 1996

Giordano P C, Harteveld C L, Kok P J, Geenen A, Batelaan D, Amons R, Bemini L F

Abstract excerpt

We describe a new alpha chain mutant accidentally found in a diabetic patient. The propositus is being treated for diabetes mellitus II with 4% glycated hemoglobin (Hb A1C). The variant, named Hb Gouda, is not detectable by starch gel electrophoresis but appears as a shoulder before the Hb A fraction during the chromatographic separation of Hb A1C. The hematological analysis revealed normal parameters with a...

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Source

Identifiers

PMID: 8745429
DOI: 10.3109/03630269609027907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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HB Gouda [alpha 72(EF1)His-->Gln], a new silent alpha chain variant.PMID 8745429Read ↗

Two new alpha chain variants: Hb Boghé [alpha58(E7)His-->Gln, alpha2], a variant on the distal histidine, and Hb CHarolles [alpha103(G10)His-Tyr, alpha1].Semantic proximity Read ↗

Hb Geldrop St. Anna [beta94(FG1)Asp --> Tyr]: a new hemoglobin variant observed in a diabetic patient.Semantic proximity Read ↗

HB Hinwil or beta 38(C4)Thr-->Asn: a new beta chain variant detected in a Swiss family.Semantic proximity Read ↗

Hb Hebei [α20 (B1) His→Leu; HBA2:C.62A > T]: A Novel Hemoglobin Variant Found during Measurement of Glycated Hemoglobin.Semantic proximity Read ↗

Characterization of a new electrophoretically silent hemoglobin variant. Hb saale OR alpha 2beta 2 84(EF8)Thr --> Ala.Semantic proximity Read ↗

Two alpha-chain hemoglobin variants, Hb Broussais and Hb Cemenelum, characterized by cation-exchange HPLC, isoelectric focusing, and peptide sequencing.Semantic proximity Read ↗

Hb Guigang [α90 (FG2)Lys→Asn; HBA1:c.273G˃T]: a Novel α-Globin Chain Variant.Semantic proximity Read ↗

Hb Gerland [alpha 55(E4)Val-->Ala]: a mutation found on the alpha1-globin gene.Semantic proximity Read ↗

Four new variants of the alpha2-globin gene without clinical or hematologic effects: Hb Park Ridge [alpha9(alpha7)Asn-->Lys (alpha2)], Hb Norton [alpha72(EF1)His-->Asp (alpha2)], Hb Lombard [alpha103(G10)His-->Tyr (alpha2)], and Hb San Antonio [A113(GH2)Leu-->Arg (A2)].Semantic proximity Read ↗

A new stable alpha chain variant: Hb Basel [alpha14(A12)Trp-->Leu (alpha1)].Semantic proximity Read ↗

Hb Aubenas [beta 62(B8)Glu-->Gly]: a new variant normally synthesized, affecting the same codon as in Hb E.Semantic proximity Read ↗

Hb Marineo [beta70(E14)Ala-->Val]: a silent hemoglobin variant with a mutation within the heme pocket.Semantic proximity Read ↗

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