Article
Spontaneous mutation rate of modifiers of metabolism in Drosophila.
Genetics - 1 Feb 1995
Clark A G, Wang L, Hulleberg T
Abstract excerpt
A rigorous test of our understanding of evolutionary quantitative genetics would be to predict accurately the equilibrium distribution of a character from empirical estimates of the relevant parameters in a mutation-selection-drift balance model. An aspect of this problem that is amenable to experimental analysis is the distribution of the effects of new mutations. This study quantifies the divergence among 200...
Topics
- Analysis of Variance
- Animals
- Biological Evolution
- Crosses, Genetic
- Drosophila melanogaster
- Enzymes
- Female
- Male
- Models, Genetic
- Mutagenesis
- Mutation