Article
Role of immune sera in the in-vitro phagocytosis of Bordetella pertussis strains.
Microbial pathogenesis - 1 Mar 2002
Stefanelli Paola, Ippoliti Rodolfo, Fazio Cecilia, Mastrantonio Paola
Abstract excerpt
In this study, phagocytosis of Bordetella pertussis was assessed using a human monocyte-derived macrophage line (THP-1) and immune sera from children who had received primary vaccination during the Italian clinical trial on the efficacy of two acellular three-component (PT-FHA-PRN) and one whole-cell pertussis vaccines. The results demonstrate that phagocytosis of opsonized bacteria with specific immune sera is...
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