Article
Genetics, molecular biology and colorectal cancer.
Mutation research - 1 Nov 1993
Finlay G J
Abstract excerpt
Colorectal cancer (CRC) develops through several histologically well-defined stages, reflecting the sequential acquisition of genetic alterations. Several frequently mutated genes have been identified which probably contribute to the development of both hereditary and sporadic cancer (reviewed in Bishop and Thomas, 1990; Fearon and Vogelstein, 1990; Fearon and Jones, 1992; Hamilton, 1992). Several generalizations...
Topics
- Animals
- Colorectal Neoplasms
- Genes, Tumor Suppressor
- Humans
- Mutation