Article
Attenuation of white gene expression in transgenic Drosophila melanogaster: possible role of a catalytic antisense RNA.
Developmental genetics - 1 Jan 1993
Heinrich J C, Tabler M, Louis C
Abstract excerpt
We have transformed Drosophila melanogaster with a DNA construct encoding a catalytic antisense RNA directed against the primary white gene RNA transcript. Total RNA isolated from transformed flies was shown to catalyze the specific cleavage of in vitro transcribed substrate RNA, indicating the e...
Topics
- Alleles
- Animals
- Animals, Genetically Modified
- Base Sequence
- DNA Transposable Elements
- Drosophila melanogaster
- Eye Color
- Gene Expression Regulation
- Genes, Insect
- Genes, Synthetic
- Heat-Shock Proteins
- Molecular Sequence Data
- Nucleic Acid Conformation
- Promoter Regions, Genetic
- RNA
- RNA Precursors
- RNA, Antisense
- RNA, Catalytic