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Article

Cofactor requirement for human immunodeficiency virus type 1 entry into a CD4-expressing human cell line

1 Oct 1993

Abstract excerpt

Expression of the human immunodeficiency virus type 1 (HIV-1) receptor CD4 on many nonhuman and some human cell lines is not sufficient to permit HIV-1 infection. We describe a human glioblastoma cell line (U373-MG) which remains resistant to HIV-1 despite the added expression of an authentic CD4 molecule. The block to HIV-1 infection of these cells is strain independent and appears to be at viral entry....

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Identifiers

PMID: 7690415
DOI: 10.1128/jvi.67.10.5939-5947.1993

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