Article
Successful application of a direct detection slide-based sequential phenotype/genotype assay using archived bone marrow smears and paraffin embedded tissue sections.
The Journal of molecular diagnostics : JMD - 1 Nov 2007
Bedell Victoria, Forman Stephen J, Gaal Karl, Pullarkat Vinod, Weiss Lawrence M, Slovak Marilyn L
Abstract excerpt
Identification of genetic abnormalities in pathological samples is critical for accurate diagnosis, risk stratification, detection of minimal residual disease, and assessment of response to therapy. Interphase fluorescence in situ hybridization analysis is the standard cytogenetic assay used by many laboratories to detect specific clonal karyotypic aberrations in formalin-fixed, paraffin-embedded tissue. However,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
