Article
Insulin production and resistance in cystic fibrosis: effect of age, disease activity, and genotype.
Journal of endocrinological investigation - 1 Mar 2012
Street M E, Spaggiari C, Ziveri M A, Rossi M, Volta C, Viani I, Grzincich G L, Sartori C, Zanzucchi M, Raia V, Terzi C, Pisi G, Zanetti E, Boguszewski M C S, Kamoi T O, Bernasconi S
Abstract excerpt
AIM: To assess the major determinants of glucose tolerance between age, genotype, and clinical status in cystic fibrosis (CF) patients, and study if defects of insulin secretion and insulin sensitivity were associated with the onset of CF-related diabetes (CFRD). SUBJECTS AND METHODS: One hundred and nineteen patients, in stable clinical condition were studied. They were subdivided into 3 groups based on age, and...
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