Article
Schistosoma japonicum: heterogeneity in paramyosin genes.
Acta tropica - 1 May 1995
Hooker C W, Yang W, Becker M M, Waine G J, Kalinna B H, Nimmo K A, McManus D P, Brindley P J
Abstract excerpt
Paramyosin is an integral muscle protein found in many invertebrates including schistosomes, and is considered an important candidate vaccine antigen in schistosomiasis. The characterisation of natural molecular variation in vaccine antigens including paramyosin is important because strain-specific vaccination may be necessary against schistosomiasis japonica. We have isolated partial cDNAs encoding paramyosin...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA, Complementary
- DNA, Helminth
- Genes, Helminth
- Genetic Heterogeneity
- Genetic Variation
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
- Restriction Mapping