Article
Evidence for clonal spread in the development of multiple meningiomas.
Journal of neurosurgery - 1 Oct 1995
Larson J J, Tew J M, Simon M, Menon A G
Abstract excerpt
Meningiomas are common intracranial tumors that arise from the arachnoid cells of the meninges. Occasionally patients develop multiple meningiomas. Because the underlying mechanism of multiple meningioma formation is unknown, the authors examined the pattern of X chromosome inactivation in multiple meningiomas. Fifteen intracranial meningiomas were resected in four patients with multiple meningiomas to determine...
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