Evidence for clonal spread in the development of multiple meningiomas.

doi:10.3171/jns.1995.83.4.0705

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Article

Evidence for clonal spread in the development of multiple meningiomas.

Journal of neurosurgery - 1 Oct 1995

Larson J J, Tew J M, Simon M, Menon A G

Abstract excerpt

Meningiomas are common intracranial tumors that arise from the arachnoid cells of the meninges. Occasionally patients develop multiple meningiomas. Because the underlying mechanism of multiple meningioma formation is unknown, the authors examined the pattern of X chromosome inactivation in multip...

Topics

Alleles
Cell Transformation, Neoplastic
DNA, Neoplasm
Female
Gene Expression Regulation, Neoplastic
Heterozygote
Humans
Meningeal Neoplasms
Meningioma
Middle Aged
Phosphoglycerate Kinase
Polymerase Chain Reaction
Receptors, Androgen
Stem Cells
X Chromosome

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