Article
Different genotypes of hepatitis C virus are associated with different severity of chronic liver disease.
Journal of medical virology - 1 Jul 1994
Pozzato G, Kaneko S, Moretti M, Crocè L S, Franzin F, Unoura M, Bercich L, Tiribelli C, Crovatto M, Santini G
Abstract excerpt
The presence of the "Japanese type" NS4 region was investigated in two series of patients (53 from Italy and 58 from Japan) with hepatitis C virus (HCV)-related chronic liver disease. The two populations were homogeneous as regard to age, male/female ratio, histological diagnosis, and serum aminotransferase activities. Genomic amplification was carried out by "nested" polymerase chain reaction (PCR) with a pair...
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