Article
Use of amplified fragment length polymorphism in molecular typing of Legionella pneumophila and application to epidemiological studies.
Journal of clinical microbiology - 1 Jul 1995
Valsangiacomo C, Baggi F, Gaia V, Balmelli T, Peduzzi R, Piffaretti J C
Abstract excerpt
A novel method for molecular typing of organisms, amplified fragment length polymorphism analysis, was tested for its suitability in epidemiological studies in medical microbiology. Amplified fragment length polymorphism analysis, originally developed for typing crop plants, consists of a simple restriction-ligation reaction and a subsequent PCR amplification. In a single-step reaction, the genomic DNA is...
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