Article
Comparative evaluation of three different genotyping methods for investigation of nosocomial outbreaks of Legionnaires' disease in hospitals.
Journal of clinical microbiology - 1 Jun 2000
Jonas D, Meyer H G, Matthes P, Hartung D, Jahn B, Daschner F D, Jansen B
Abstract excerpt
The increased incidence of nosocomial Legionnaires' disease in two hospitals prompted investigation of possible environmental sources. In the search for an effective DNA-typing technique for use in hospital epidemiology, the performance and convenience of three methods-SfiI macrorestriction analysis (MRA), amplified fragment length polymorphism (AFLP), and arbitrarily primed PCR (AP-PCR)-were compared....
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