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Article

Cloning of the gene encoding TROP‐2, a cell‐surface glycoprotein expressed by human carcinomas

4 Sept 1995

Abstract excerpt

We have cloned by expression the cDNA encoding Trop-2, a cell-surface glycoprotein expressed by most human carcinomas. Formal proof of the identity of the clone is the hybridization to DNA and RNA from genomic TROP2 transfectants. TROP2 is a single-copy gene in human cells, hybridizes to a single 1.8-kb mRNA from expressing sources and encodes a 35,709 Da type-1 transmembrane protein with a single transmembrane...

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Identifiers

PMID: 7665234
DOI: 10.1002/ijc.2910620520

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Cloning of the gene encoding TROP‐2, a cell‐surface glycoprotein expressed by human carcinomasPMID 7665234Read ↗

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