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Article

Genomic organization of the human osteopontin gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II.

Genomics - 1 May 1995

Crosby A H, Edwards S J, Murray J C, Dixon M J

Abstract excerpt

Osteopontin (SPP1) is the principal phosphorylated glycoprotein of bone that is also expressed in a limited number of other tissues including dentine. In the current investigation we report the genomic organization of the SPP1 gene, which comprises seven exons, six of which contain coding sequence. The splice sites for exon donor and acceptor positions are in close agreement with previously published consensus...

Topics

Alleles
Base Sequence
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 4
Dentinogenesis Imperfecta
Genes
Genes, Dominant
Humans
Lod Score
Molecular Sequence Data
Osteopontin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sialoglycoproteins

Source

Identifiers

PMID: 7665163
DOI: 10.1006/geno.1995.1018

Genes

SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7665163-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Genomic organization of the human osteopontin gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II.PMID 7665163Read ↗

Elucidation of the sequence and the genomic organization of the human dentin matrix acidic phosphoprotein 1 (DMP1) gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II.Semantic proximity Read ↗

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