Article
Polymorphism of factor H (beta 1H globulin) in Japanese: description of a new allele.
Gene geography : a computerized bulletin on human gene frequencies - 1 Dec 1994
Kido A, Kimura Y, Nishizono T, Oya M, Shiozawa Z
Abstract excerpt
Polymorphism of factor H (HF) was investigated in 1060 unrelated Japanese individuals using isoelectric focusing and immunoblotting. Besides 6 different HF types a null type and an unusual type were observed. The family analysis suggested the hereditary occurrence of a new variant allele HF*C. The population data fitted the Hardy-Weinberg equilibrium, assuming that the null allele HF*QO occurs commonly. The...
Topics
- Alleles
- Complement Factor H
- Female
- Gene Frequency
- Humans
- Immunoblotting
- Isoelectric Focusing
- Japan
- Male
- Pedigree
- Phenotype
- Polymorphism, Genetic