Article
Factor H gene variants in Japanese: its relation to atypical hemolytic uremic syndrome.
Molecular immunology - 1 Oct 2011
Mukai Saki, Hidaka Yoshihiko, Hirota-Kawadobora Masako, Matsuda Kazuyuki, Fujihara Noriko, Takezawa Yuka, Kubota Seiko, Koike Kenichi, Honda Takayuki, Yamauchi Kazuyoshi
Abstract excerpt
Mutations and polymorphisms of factor H gene (FH1) are known to be closely involved in the development of atypical hemolytic uremic syndrome (aHUS). Several groups have identified disease risk mutations and polymorphisms of FH1 for the development of aHUS, and have investigated frequencies of aHUS in a number of ethnic groups. However, such studies on Japanese populations are limited. In the present study, we...
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