Article
The Aspergillus uvsH gene encodes a product homologous to yeast RAD18 and Neurospora UVS-2.
Molecular & general genetics : MGG - 28 Jul 1995
Yoon J H, Lee B J, Kang H S
Abstract excerpt
The uvsH DNA repair gene of Aspergillus nidulans has been cloned by complementation of the uvsH77 mutation with a cosmid library containing genomic DNA inserts from a wild-type strain. Methylmethane sulfonate (MMS)-resistant transformants were obtained on medium containing 0.01% MMS, to which uvsH mutants exhibit high sensitivity. Retransformation of uvsH77 mutants with the rescued cosmids from the MMS-resistant...
Topics
- Alleles
- Amino Acid Sequence
- Aspergillus nidulans
- Base Sequence
- Cloning, Molecular
- Conserved Sequence
- DNA Repair
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
