Article
An association study between essential hypertension and HLA-DRB1 alleles.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Jun 1995
Tao Z, Zhao Y, Zhu X, Zhu K, Yu G, Wu W, Dong Y, Liu L, Qiu C
Abstract excerpt
It is well established that genetic and environmental factors are involved in the etiology of essential hypertension (EH). Previous studies have suggested that at least one of the HLA genes is responsible for the genetic susceptibility to EH. Our aim in the present study was to investigate this issue in China by the PCR-SSP HLA-DRB1 typing method. The results showed an increased frequency of HLA-DR2 and a...
Topics
- Alleles
- Asian People
- China
- Disease Susceptibility
- Female
- Gene Frequency
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Hypertension
- Male
- Middle Aged