Article
HLA-DQB1 allele associates with idiopathic nephrotic syndrome in Japanese children.
Acta paediatrica Japonica : Overseas edition - 1 Jun 1995
Kobayashi T, Ogawa A, Takahashi K, Uchiyama M
Abstract excerpt
HLA-DQA1 and -DQB1 genes were investigated in 30 Japanese children with idiopathic nephrotic syndrome (INS) using the polymerase chain reaction-restriction fragment length polymorphism method. Compared with control children, there was a significant increase in the HLA-DQA1*0501, DQB1*0301 and DQB1*0601 alleles, whereas the frequency of DQB1*0501 showed a significant decrease in the patients. The increase of...
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