HLA-DQB1 allele associates with idiopathic nephrotic syndrome in Japanese children.

doi:10.1111/j.1442-200x.1995.tb03317.x

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Article

HLA-DQB1 allele associates with idiopathic nephrotic syndrome in Japanese children.

Acta paediatrica Japonica : Overseas edition - 1 Jun 1995

Kobayashi T, Ogawa A, Takahashi K, Uchiyama M

Abstract excerpt

HLA-DQA1 and -DQB1 genes were investigated in 30 Japanese children with idiopathic nephrotic syndrome (INS) using the polymerase chain reaction-restriction fragment length polymorphism method. Compared with control children, there was a significant increase in the HLA-DQA1*0501, DQB1*0301 and DQB...

Topics

Adolescent
Alleles
Amino Acid Sequence
Case-Control Studies
Child
Child, Preschool
Disease Susceptibility
Female
Genes, MHC Class II
Humans
Japan
Male
Molecular Sequence Data
Nephrotic Syndrome
Polymerase Chain Reaction

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