Article
Tetrapac (tpc), a novel genotype of Neisseria gonorrhoeae affecting epithelial cell invasion, natural transformation competence and cell separation.
Molecular microbiology - 1 Mar 1996
Fussenegger M, Kahrs A F, Facius D, Meyer T F
Abstract excerpt
We characterized a novel mutant phenotype (tetrapac, tpc) of Neisseria gonorrhoeae (Ngo) associated with a distinctive rough-colony morphology and bacterial growth in clusters of four. This phenotype, suggesting a defect in cell division, was isolated from a mutant library of Ngo MS11 generated w...
Topics
- Amino Acid Sequence
- Bacterial Adhesion
- Base Sequence
- Cell Division
- Cell Line
- DNA, Bacterial
- Epithelium
- Genes, Bacterial
- Genetic Complementation Test
- Genotype
- Humans
- Molecular Sequence Data
- Mutation
- N-Acetylmuramoyl-L-alanine Amidase
- Neisseria gonorrhoeae
- Phenotype
- Plasmids
- Promoter Regions, Genetic