Article
Mechanisms of immature myocardial tolerance to ischemia: phenotypic differences in antioxidants, stress proteins, and oxidases.
Surgery - 1 Aug 1995
Rowland R T, Meng X, Ao L, Terada L S, Harken A H, Brown J M
Abstract excerpt
BACKGROUND: Previous work has suggested tolerance to ischemic injury in newborn myocardium. Although various mechanisms for this protection have been proposed, a link between oxidant-antioxidant factors, stress protein expression, and protection from cardiac ischemia/reperfusion (I/R) injury has...
Topics
- Aging
- Animals
- Animals, Newborn
- Antioxidants
- Blood Pressure
- Catalase
- Diastole
- HSP72 Heat-Shock Proteins
- Heart
- Heat-Shock Proteins
- Male
- Myocardial Ischemia
- Myocardium
- Oxidoreductases
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Ventricular Function, Left