Article
Biochemical characterization of Sinorhizobium meliloti mutants reveals gene products involved in the biosynthesis of the unusual lipid A very long-chain fatty acid.
The Journal of biological chemistry - 20 May 2011
Haag Andreas F, Wehmeier Silvia, Muszyński Artur, Kerscher Bernhard, Fletcher Vivien, Berry Susan H, Hold Georgina L, Carlson Russell W, Ferguson Gail P
Abstract excerpt
Sinorhizobium meliloti forms a symbiosis with the legume alfalfa, whereby it differentiates into a nitrogen-fixing bacteroid. The lipid A species of S. meliloti are modified with very long-chain fatty acids (VLCFAs), which play a central role in bacteroid development. A six-gene cluster was hypothesized to be essential for the biosynthesis of VLCFA-modified lipid A. Previously, two cluster gene products, AcpXL...
Topics
- Acyl Carrier Protein
- Bacterial Proteins
- Escherichia coli
- Fabaceae
- Fatty Acids
- Lipid A
- Mutation
- Sinorhizobium meliloti
- Symbiosis