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Article

Expression and <i>in‐situ</i> localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer

9 Aug 1995

Abstract excerpt

Pancreatic cancer shows a strong desmoplastic reaction characterized by a remarkable proliferation of interstitial connective tissue (collagens type I and III, fibronectin). In this study we have analyzed the balance of expression of mRNAs encoding extracellular matrix components (collagens I, III and IV, laminin, fibronectin), extracellular matrix-degrading metalloproteinases (MMP-1, -2, -3 and -9) and tissue...

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PMID: 7635566
DOI: 10.1002/ijc.2910620409

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