Article
The elucidation of novel capsular genotypes of Haemophilus influenzae type b with the polymerase chain reaction.
Journal of medical microbiology - 1 Aug 1995
Leaves N I, Falla T J, Crook D W
Abstract excerpt
Molecular characterization is an important pre-requisite for post-vaccine studies of Haemophilus influenzae type b (Hib). Three capsular genotyping patterns, b(S), b(G) and b(V), have been described in the major phylogenetic lineage of Hib. However, in a recent series of prospective studies, three new hybridisation patterns were observed among 425 strains of Hib. Four pairs of polymerase chain reaction (PCR)...
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