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Article

DNA polymorphism and molecular subtyping of the capsular gene cluster of group B streptococcus.

Journal of clinical microbiology - 1 Dec 2005

Manning Shannon D, Lacher David W, Davies H Dele, Foxman Betsy, Whittam Thomas S

Abstract excerpt

Serotyping and other phenotypic methods are often used to characterize the capsular polysaccharide of group B streptococci (GBS). We describe a capsular genotyping method that utilizes PCR of capsular polysaccharide synthesis genes (cps) and restriction enzyme digestion. This method facilitates the detection of DNA polymorphism in cps genes and correlates well with serotyping.

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Identifiers

PMID: 16333106
DOI: 10.1128/JCM.43.12.6113-6116.2005
PMCID: PMC1317180

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