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Article

Leber's "plus": neurological abnormalities in patients with Leber's hereditary optic neuropathy.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 1995

Nikoskelainen E K, Marttila R J, Huoponen K, Juvonen V, Lamminen T, Sonninen P, Savontaus M L

Abstract excerpt

Previous studies suggest that Leber's hereditary optic neuropathy (LHON) may be a systemic disorder with manifestations in organs other than the optic nerves. To evaluate nervous system involvement 38 men and eight women with LHON were re-examined. The patients were divided into three groups according to mtDNA analysis--namely, patients with the 11778 or with the 3460 mutation and patients without these primary...

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Identifiers

PMID: 7629530
DOI: 10.1136/jnnp.59.2.160
PMCID: PMC485991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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