Article
Plasmodium falciparum: variations within the C-terminal region of merozoite surface antigen-1.
Experimental parasitology - 1 Aug 1995
Tolle R, Bujard H, Cooper J A
Abstract excerpt
Sequence variations at the 3'-end of the Plasmodium falciparum merozoite surface antigen-1 gene show that the C-terminus of the protein may not be as conserved as has been assumed in the past. We have therefore examined the sequences of the 3' terminal 2 kb, i.e., blocks 12-17 of four isolates, RO-33, RO-71, 3D7A, and FCH5. We discuss different mechanisms of genetic exchange that could account for the observed...
Topics
- Animals
- Antigens, Protozoan
- Base Sequence
- Conserved Sequence
- DNA Primers
- DNA, Protozoan
- Genetic Variation
- Merozoite Surface Protein 1
- Molecular Sequence Data
- Plasmodium falciparum
- Polymerase Chain Reaction