Article
A significant beta-thalassemia heterogeneity in the United Arab Emirates.
Hemoglobin - 1 May 1997
el-Kalla S, Mathews A R
Abstract excerpt
The Dubai Thalassemia Center has identified 35 different beta-thalassemia mutations in 570 chromosomes from the United Arab Emirates population using gene amplification, hybridization with specific labeled oligonucleotide probes, sequencing of amplified DNA, restriction enzymes, and amplification...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Chromosomes, Human
- Consensus Sequence
- Exons
- Female
- Frameshift Mutation
- Genes, Dominant
- Genetic Heterogeneity
- Humans
- Infant
- Infant, Newborn
- Introns
- Male
- Mutation
- Point Mutation