Proton-translocating nicotinamide nucleotide transhydrogenase of Escherichia coli. Involvement of aspartate 213 in the membrane-intercalating domain of the beta subunit in energy transduction.

doi:10.1074/jbc.270.28.16653

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Article

Proton-translocating nicotinamide nucleotide transhydrogenase of Escherichia coli. Involvement of aspartate 213 in the membrane-intercalating domain of the beta subunit in energy transduction.

The Journal of biological chemistry - 14 Jul 1995

Yamaguchi M, Hatefi Y

Abstract excerpt

Mutations in the beta subunit of Escherichia coli proton-translocating nicotinamide nucleotide transhydrogenase of the conserved residue beta Asp-213 to Asn (beta D213N) and Ile (beta D213I) resulted in the loss, respectively, of about 70% and 90% NADPH-->3-acetylpyridine adenine dinucleotide (Ac...

Topics

Amino Acid Sequence
Escherichia coli
Molecular Sequence Data
Mutation
NAD
NADP
NADP Transhydrogenases
Structure-Activity Relationship

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