Article
[Interrelationship between structural variants of the apolipoprotein B and ischemic heart disease and plasma lipid levels].
Genetika - 1 Mar 1995
Stepanov V A, Puzyrev V P, Lemza S V, Karpov R S, Fedorov A Iu
Abstract excerpt
Xba I and EcoR I polymorphism of the apolipoprotein B (APOB) gene was studied by PCR. A significant increase in the frequency of allele X+ and haplotype H+E+ was demonstrated in patients with coronarographically documented coronary heart disease (CHD) over that of the general population. Associat...
Topics
- Adult
- Alleles
- Apolipoproteins B
- Case-Control Studies
- Coronary Disease
- Gene Frequency
- Genetic Markers
- Genetic Variation
- Haplotypes
- Humans
- Lipids
- Male
- Middle Aged
