Primary midline developmental field. I. Clinical and epidemiological characteristics

Abstract excerpt

Abstract Opitz [BD: OAS XXIX(1): 3‐37, 1993] has postulated that during early blastogenesis the entire embryo represents a single morphogenetic unit, the primary field. During this period, beginning gastrulation, the most important events are the formation of the midline and the mesoderm. Consequently, one could expect that dysmorphogenetic reactions of the primary field are likely to disturb more than one of the...

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