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Article

Mapping a gene causing cerebral cavernous malformation to 7q11.2-q21.

3 Jul 1995

Abstract excerpt

Cerebral cavernous malformation is a common disease of the brain vasculature of unknown cause characterized by dilated thin-walled sinusoidal vessels (caverns); these lesions cause varying clinical presentations which include headache, seizure, and hemorrhagic stroke. This disorder is frequently familial, with autosomal dominant inheritance. Using a general linkage approach in two extended cavernous malformation...

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Share to Intracerebral and Subarachnoid Hemorrhage Research
Share to Intracranial Aneurysms: Treatment and Complications
Share to Vascular Malformations Diagnosis and Treatment

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Identifiers

PMID: 7604043
DOI: 10.1073/pnas.92.14.6620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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Mapping a gene causing cerebral cavernous malformation to 7q11.2-q21.PMID 7604043Read ↗

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Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1).Semantic proximity Read ↗

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