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Article

Linkage to the CCM2 locus and genetic heterogeneity in familial cerebral cavernous malformation.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 May 2003

Dupré Nicolas, Verlaan Dominique J, Hand Collette K, Laurent Sandra B, Turecki Gustavo, Davenport W Jeptha, Acciarri Nicola, Dichgans Johannes, Ohkuma Akio, Siegel Adrian M, Rouleau Guy A

Abstract excerpt

BACKGROUND: Cerebral cavernous malformation (CCM) is a form of intracranial vascular disease that may arise sporadically or be dominantly inherited. Linkage studies have revealed genetic heterogeneity among the dominantly inherited forms suggesting the existence of at least three loci called CCM1, CCM2 and CCM3. METHODS: In the present study, we screened five families with dominantly inherited CCM for CCM1 gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hemangioma, Cavernous, Central Nervous System

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Source

Identifiers

PMID: 12774951
DOI: 10.1017/s0317167100053385

Genes

CCM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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