Article
A study of the double mutation of dnaJ and cbpA, whose gene products function as molecular chaperones in Escherichia coli.
Journal of bacteriology - 1 Jul 1995
Ueguchi C, Shiozawa T, Kakeda M, Yamada H, Mizuno T
Abstract excerpt
The CbpA protein is an analog of the DnaJ molecular chaperone of Escherichia coli. To gain insight into the function of CbpA, we examined the nature of a cbpA null mutation with special reference to those of dnaK and dnaJ null mutations. In particular, the cbpA dnaJ double-null mutant was found to exhibit severe defects in cell growth, namely, a very narrow temperature range for growth, a defect in cell division,...
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