Article
The rpoD gene functions as a multicopy suppressor for mutations in the chaperones, CbpA, DnaJ and DnaK, in Escherichia coli.
FEMS microbiology letters - 1 May 1996
Shiozawa T, Ueguchi C, Mizuno T
Abstract excerpt
The CbpA protein is an analog of the DnaJ molecular chaperone of Escherichia coli. The dnaJ- cbpA- double-null mutant exhibits severe defects in cell growth, namely, a very narrow temperature range for growth. To gain insight into the functions of CbpA as well as DnaJ, we isolated a multicopy suppressor gene that permits this dnaJ- cbpA- mutant to grow normally at low temperatures. The suppressor gene was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.