Article
The rpoD gene functions as a multicopy suppressor for mutations in the chaperones, CbpA, DnaJ and DnaK, in Escherichia coli.
FEMS microbiology letters - 1 May 1996
Shiozawa T, Ueguchi C, Mizuno T
Abstract excerpt
The CbpA protein is an analog of the DnaJ molecular chaperone of Escherichia coli. The dnaJ- cbpA- double-null mutant exhibits severe defects in cell growth, namely, a very narrow temperature range for growth. To gain insight into the functions of CbpA as well as DnaJ, we isolated a multicopy sup...
Topics
- Bacterial Proteins
- DNA-Binding Proteins
- DNA-Directed RNA Polymerases
- Escherichia coli
- Escherichia coli Proteins
- Gene Amplification
- Genes, Bacterial
- HSP40 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Molecular Chaperones
- Mutation
- Sigma Factor
- Suppression, Genetic